Fencamfamine - Infogalactic: the planetary knowledge core.
Fencamfamin (), also known as fencamfamine or by the brand names Glucoenergan and Reactivan, is a stimulant which was developed by Merck in the 1960s. (2) Contents. Medical uses; Adverse effects; Contraindications; Overdose; Research; Synthesis; See also; References; Medical uses. Fencamfamin is still used, though rarely, for treating depressive day-time fatigue, lack of concentration and.
Here we report an efficient synthesis of sulfamides. 3,5-Lutidine was found to be an optimal solvent and catalyst for the reaction. The method was developed during our efforts to synthesize a series of novel FKBP-12 inhibitors in which the known ketoamide linker was replaced with sulfamide.
Flutamide has been synthesised conveniently in high yields and by an economically beneficial method. Benzotrifluoride was first nitrated and the product was reduced and acylated in one pot in the.
Editor-In-Chief: C. Michael Gibson, M.S., M.D. Overview. Fencamfamine (Glucoenergan, Reactivan) is a stimulant which was developed in the 1960s as an appetite suppressant, but was later withdrawn for this application due to problems with dependence and abuse.It is around half the potency of dexamphetamine, and is prescribed at a dose of 10-60mg, although abusers of the drug tend to rapidly.
Camfetamine (CFA) is also known as N-methyl-3-phenyl-norborna n-2-amine. It is an analogue of fencamfamine. In the central nervous system, camfetamine may serve as an indirect dopaminergic agonist and may also possess mild-moderate opioid activity. It also acts as an amphetamine-type stimulant to psychoactive substances.
Fosfomycin ((1R,2S)-epoxypropylphosphonate, pictured) is an antibiotic used to treat gastrointestinal and urinary infections. Its pharmacological function depends on its epoxide ring. In bacteria, this group is formed in a reaction catalyzed by S-HPP epoxidase (HppE), an iron-dependent enzyme that converts (S)-2-hydroxypropyl-1-phosphonate (S-HPP) into fosfomycin.
Fosfomycin synthesis. Comment and reaction mechanism It's a particularly efficient synthesis, very easy from a practical point of view. There is not any intermediate operation of purification since almost the entire reaction is carried on in just one solvent (benzene). The first.